Pediatrics, Growth, and Airway-Centered Development

Early-life breathing and sleep patterns shape growth, behavior, learning, and craniofacial development—supporting early screening and intervention.

  • A Review of 50 Children With Obstructive Sleep Apnea Syndrome.

    Guilleminault C, Korobkin R, Winkle R.

    Establishes pediatric OSA as a cause of behavioral issues, enuresis, learning difficulties, and growth disturbance.

    [Pediatrics (1981)]

  • Nocturnal Pulse Oximetry as an Abbreviated Testing Modality for Pediatric Obstructive Sleep Apnea.

    Brouillette RT, et al.

    Demonstrates early recognition of pediatric sleep-disordered breathing without reliance on adult criteria.

    [Pediatrics (2000)]

  • Symptoms of Sleep Disorders, Inattention, and Hyperactivity in Children.

    Chervin RD, et al.

    Links sleep-disordered breathing to ADHD-like symptoms and executive dysfunction.

    [Sleep (2002)]

  • Sleep-Disordered Breathing and School Performance in Children.

    Gozal D.

    Shows that untreated SDB negatively impacts cognitive performance and academic outcomes.

    [Pediatrics (1998)]

  • Neurobehavioral Morbidity Associated With Disordered Breathing During Sleep in Children.

    Beebe DW.

    Reviews mechanisms linking hypoxia and sleep fragmentation to neurocognitive deficits.

    [Sleep (2006)]

  • Growth and Growth Biomarker Changes After Adenotonsillectomy for OSA.

    Bonuck K, Freeman K, Henderson J.

    Demonstrates catch-up growth after treatment of pediatric airway obstruction.

    [Pediatrics (2009)]

  • Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome.

    Marcus CL, et al.

    AAP clinical guideline establishing pediatric OSA as a medical condition requiring early identification.

    [Pediatrics (2012)]

  • Obstructive Sleep Apnea Syndrome in Children and Adolescents: Orthodontic Perspectives.

    Pirelli P, Saponara M, Attanasio G.

    Links maxillary constriction, narrow palates, and craniofacial growth to pediatric airway obstruction.

    [European Journal of Paediatric Dentistry (2004)]

  • Efficacy of Rapid Maxillary Expansion in Children With Obstructive Sleep Apnea Syndrome.

    Villa MP, et al.

    Shows orthodontic expansion improves airway function and sleep parameters.

    [American Journal of Respiratory and Critical Care Medicine (2007)]

  • Primate Experiments on Oral Respiration.

    Harvold EP, Vargervik K, Chierici G.

    Demonstrates that nasal obstruction during growth alters craniofacial development.

    [American Journal of Orthodontics (1981)]

  • Adenoids: Their Effect on Mode of Breathing and Nasal Airflow.

    Linder-Aronson S.

    Classic work showing mouth breathing alters facial growth and dental arch development.

    [Acta Otolaryngologica (1970)]

  • Mouth Breathing Children: Facial Characteristics and Airway Dimensions.

    Souki BQ, et al.

    Links chronic mouth breathing to long, narrow faces and altered craniofacial proportions.

    [Dental Press Journal of Orthodontics (2009)]

  • Nocturnal Enuresis in Children With Sleep Apnea.

    Weider DJ, Hauri PJ.

    Demonstrates strong association between bedwetting and sleep-disordered breathing.

    [American Journal of Otolaryngology (1985)]

  • Enuresis in Children With Sleep Apnea.

    Brooks LJ, Topol HI.

    Shows resolution of enuresis following treatment of airway obstruction.

    [Journal of Pediatrics (2003)]

  • Otitis Media and Mouth Breathing.

    Ysunza A, et al.

    Links nasal obstruction and mouth breathing to recurrent otitis media and conductive hearing loss.

    [International Journal of Pediatric Otorhinolaryngology (2008)]

  • Upper Airway Resistance Syndrome in Children.

    Guilleminault C, et al.

    Shows that children can have significant sleep-related breathing pathology without classic apnea.

    [Chest (2004)]

  • Craniofacial Morphology and Pediatric Obstructive Sleep Apnea.

    Katyal V, et al.

    Demonstrates relationships between facial structure, airway size, and pediatric OSA risk.

    [Sleep Medicine Reviews (2013)]

  • A Clinical Guide to Pediatric Sleep.

    Mindell JA, Owens JA.

    Comprehensive clinical reference emphasizing early sleep and airway intervention.

    [Lippincott Williams & Wilkins (2015)]

  • Pediatric Airway: Early Recognition and Intervention.

    Olmos S.

    Outlines how pediatric airway obstruction presents as behavioral, developmental, and growth-related concerns, emphasizing early identification to prevent long-term sequelae.

    [Orthodontic Practice US (2017)]

  • Airway-Centered Orthodontics in the Pediatric Patient.

    Olmos S.

    Describes the role of orthodontic and airway evaluation in children with sleep-disordered breathing, ADHD-like symptoms, and craniofacial growth concerns.

    [Orthodontic Practice US (2018)]

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https://pubmed.ncbi.nlm.nih.gov/7213977/
https://pubmed.ncbi.nlm.nih.gov/10742347/
https://pubmed.ncbi.nlm.nih.gov/12003157/
https://pubmed.ncbi.nlm.nih.gov/9504264/
https://pubmed.ncbi.nlm.nih.gov/16774152/
https://pubmed.ncbi.nlm.nih.gov/19706561/
https://pubmed.ncbi.nlm.nih.gov/22926173/
https://pubmed.ncbi.nlm.nih.gov/15366625/
https://pubmed.ncbi.nlm.nih.gov/17556720/
https://pubmed.ncbi.nlm.nih.gov/1056945/
https://pubmed.ncbi.nlm.nih.gov/5470042/
https://pubmed.ncbi.nlm.nih.gov/20567654/
https://pubmed.ncbi.nlm.nih.gov/4000432/
https://pubmed.ncbi.nlm.nih.gov/12970609/
https://pubmed.ncbi.nlm.nih.gov/18621430/
https://pubmed.ncbi.nlm.nih.gov/14769725/
https://pubmed.ncbi.nlm.nih.gov/23040358/
https://www.wolterskluwer.com/en/solutions/ovid/a-clinical-guide-to-pediatric-sleep-2006
https://orthopracticeus.com/industry-news/pediatric-airway-early-recognition-and-intervention/