Psychiatry, Mood, and ADHD
Sleep fragmentation and airway stress can present as anxiety, irritability, inattention, and hyperactivity—supporting airway screening when symptoms are persistent or treatment-resistant.
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Attention Deficit Hyperactivity Disorder and Sleep Disordered Breathing in Pediatric Populations: A Meta-Analysis.
Sedky K, Bennett DS, Carvalho KS.
Shows a significant association between pediatric sleep-disordered breathing and ADHD symptoms, supporting airway screening in children presenting with attention and behavior concerns.
[Sleep Medicine Reviews, 2014]
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Sleep-Disordered Breathing and Neurobehavioral Deficits in Children and Adolescents: a Systematic Review and Meta-Analysis.
Zhang W, Shen Y, Ou X, Wang H, Liu S.
Quantifies neurobehavioral impacts linked to pediatric sleep-disordered breathing, reinforcing that behavior and mood symptoms can be downstream of sleep physiology.
[BMC Pediatrics, 2024]
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Sleep-Disordered Breathing in a Population-Based Cohort: Behavioral Outcomes at 4 and 7 years.
Bonuck K, Freeman K, Chervin RD, Xu L.
Population cohort data linking early-life sleep-disordered breathing trajectories to later behavioral difficulties, supporting early screening rather than “wait and see.”
[Pediatrics, 2012]
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Effects of Continuous Positive Airway Pressure on Depression and Anxiety Symptoms in Patients with Obstructive Sleep Apnoea: Results from the SAVE Trial and Meta-Analysis.
Zheng D, Xu Y, You S, et al.
Shows CPAP improves depressive symptoms (and clarifies more mixed findings for anxiety), supporting airway treatment as part of mood care when OSA is present.
[eClinicalMedicine, 2019]
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Effect of Treatment of Obstructive Sleep Apnea on Depressive Symptoms: Systematic Review and Meta-Analysis.
Schwartz DJ, Karatinos G.
RCT meta-analysis demonstrating improvement in depressive symptoms with CPAP and mandibular advancement devices, positioning airway treatment as an adjunct to depression care, not a replacement.
[PLOS Medicine, 2015]
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Sleep-Disordered Breathing in Children
AAP Clinical Review.
Connects pediatric nasal obstruction to sleep-disordered breathing, reinforcing the need for nasal assessment before labeling symptoms as behavioral or neurologic.
[Pediatrics in Review, 2019]
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https://archive.org/download/Bok3A978-0-387-23692-6/1-s2.0-S1087079213001329-main.pdf
https://link.springer.com/article/10.1186/s12887-023-04511-2
https://doi.org/10.1542/peds.2011-1402
https://doi.org/10.1016/j.eclinm.2019.05.012
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001762
https://publications.aap.org/pediatricsinreview/article/40/1/3/35201/Sleep-Disordered-Breathing-in-Children